Genetic and environmental factors play an important role in the occurrence of obesity. Diet is one of the main environmental factors that induce obesity and related metabolic diseases. Studies have shown that the continuous growth of fat intake is easy to cause weight gain, which leads to obesity and its related metabolic diseases. Rodents have significant weight gain when fed with high-fat diet, so rodent model is widely used in the study of the pathogenesis and treatment of diet induced obesity (DIO).
